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学术报告-Structure-Based Drug Design and Discovery of Phosphodiesterase-5 Inhibitors for Treatment of Human Disease

来源:元素有机化学国家重点实验室   发布时间:2017/04/25


学术报告题目:Structure-Based Drug Design and Discovery of Phosphodiesterase-5 Inhibitors for Treatment of Human Disease

 

报告人:Prof. Hengming Ke (柯衡明)

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, USA

 

时间:2017年4月28日(星期五)上午10:30

 

地点:第六教学楼 222会议室 

 

 

报告人简介

Prof Hengming Ke (Research Field: X-ray Protein Crystallography and Biochemistry)

 

1976: B.S. from Zhongshan University

1989: Ph.D. from Harvard University

1990-2000: Associate Professor, University of North Carolina at Chapel Hill

2001-Present: Professor, University of North Carolina at Chapel Hill

 

His research focuses on the structure and function of medically important proteins, and structure-based design of inhibitors for treatment of human diseases. The current topics include enzymatic and structural characterization of cyclic nucleotide phosphodiesterases (PDEs), structure-based design of PDE selective inhibitors, and discovery of novel metallo-β-lactamase (MBL) inhibitors to fight against superbugs.

 

Group Page: http://www.med.unc.edu/biochem/people/faculty/primary/ke