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南开大学元素有机重点实验室

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李茂霖   特聘研究员    

Dr. Mao-Lin Li                

E-mail: maolin@nankai.edu.cn

Group Home Page: https://www.x-mol.com/groups/maolin        


 

Education   

2014-2019    Organic Chemistry, Nankai University, Tianjin, China (with Prof. Qi-Lin Zhou).

2010-2014    Material Chemistry, Nankai University, Tianjin, China


Academic Career

2025-            Principal Investigator, State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

2021-2025    Postdoctoral associate, Center for Advanced Bioenergy and Bioproducts Innovation University of Illinois at Urbana-Champaign, Urbana, IL, USA (with Prof. Huimin Zhao)

2020-2021    Postdoctoral associate, State Key Laboratory and Institute of Elemento-Organic Chemistry Nankai University, Tianjin, China (with Prof. Qi-Lin Zhou)

                           

Research Areas

(1)    Synthetic Biology, Biocatalysis, Photocatalysis

(2)    Computation, Automation, Machine Learning



Selected Publications

  1. Zhang, Z.†; Li, M.-L.†; Harrison, W.; Lu, J.; Zhao, Z.; Yuan, Y.; Zhao, H.* Photoenzymatic Stereoablative Enantioconvergence of γ-Chiral Oximes via Hydrogen Atom Transfer. Nat. Catal. 2025, Accepted. (†Contribute Equally)

  2. Li, M.-L.; Yuan, Y.; Harrison, W.; Zhang, Z.; Zhao, H.* Asymmetric Photoenzymatic Incorporation of Fluorinated Motifs into Olefins. Science 2024, 385, 416-421

  3. Li, M.-L.; Harrison, W.; Zhang, Z.; Yuan, Y.; Zhao, H.* Remote Stereocontrol with Azaarenes via Enzymatic Hydrogen Atom Transfer. Nat. Chem. 2024, 16, 277-284.

  4. Pan, J.-B.; Zhang, X.-G.; Shi, Y.-F.; Han, A.-C.; Chen, Y.-J.; Ouyang, J.; Li, M.-L.*; Zhou, Q.-L.*, A Spiro Phosphamide Catalyzed Enantioselective Proton Transfer of Ylides in a Free Carbene Insertion into N−H Bonds. Angew. Chem. Int. Ed. 2023, 62, e202300691.

  5. Li, M.-L.†; Pan, J.-B.†; Zhou, Q.-L.* Enantioselective Synthesis of Amino Acids from Ammonia. Nat. Catal. 2022, 5, 571–577. (†Contribute Equally)

  6. Li, M.-L.; Yu, J.-H.; Li, Y.-H.; Zhu, S.-F.*; Zhou, Q.-L.* Highly Enantioselective Carbene Insertion into N–H Bonds of Aliphatic Amines. Science 2019, 366, 990–994.