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南开大学元素有机重点实验室

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苗志伟  教授     

Prof. Zhiwei Miao (Z.-W. Miao)      

Tel: 86-22-23503192        

E-mail: miaozhiwei@nankai.edu.cn

Group Home Page: http://skleoc.nankai.edu.cn/info/1018/4422.htm        


 

Education   

1999-2002    Department of Chemistry, Tsinghua University, Beijing, China. Received PhD degree in July, 2002 (with Prof. Yu-Fen Zhao).  

1994-1998    Department of Chemistry, Tianjin Normal University. Tianjin, CHINA. Received MS degree in March, 1998 (with Prof. Fang-Ming Miao)    

1987-1991    Department of Chemistry, Tianjin Normal University, Tianjin, CHINA. Received BSc Degree in July, 1991.

 

Academic Career                                

2012-         Professor, Institute of Elemento-organic Chemistry, State Key Laboratory of Elemento-organic Chemistry, Nankai                                 University, Tianjin, CHINA. 

2004-2011 Associate Professor, Institute of Elemento-organic Chemistry, State Key Laboratory of Elemento-organic Chemistry,                             Nankai University, Tianjin, CHINA.

2002-2004 Postdoctoral associate, Department of Chemistry, ETH Zürich, Switzerland (with Prof. Andrea Vasella).

1998-1999 Assistant Professor, Department of Chemistry, Tianjin Normal University, Tianjin, CHINA.


Research Areas

(1)     Organic phosphorus chemistry and Asymmetric synthesis chemistry

(2)     Applied organic chemistry and Agriculture chemistry


Honors & Awards 
2014    Award for “Xinjiang Tianshan Scholar” (the Xinjiang Uygur Autonomous Region of China)

2018    Award for “Nankai University Teaching Famous Teacher Award”


Professional Memberships 

2022-  Member, Chemical Fertilizer Professional Committee of China Chemical Society.


Representative Achievements

Selected Publications (2017-present)

  1. Yanfeng Gao, Xuange Zhang, Xiyuan Zhang, and Zhiwei Miao* “Catalytic Asymmetric Construction of 1,2,4-Benzotriazepine Skeleton via Diastereo- and Enantioselective Decarboxylative [4+3] Cyclization” Org. Lett. 2021, 23, 2415-2420.

  2. Xiyuan Zhang, Yanfeng Gao, Yitong Liu, and Zhiwei Miao* “Diastereoselective Synthesis of Tetrabenzohydrofuran Spirooxindoles via Diethylphosphite-mediated Coupling of isatins with ortho-Quinone Methides” J. Org. Chem. 2021, 86, 8630-8640.

  3. Yan Cai, Jing Meng, Weihong Zhou, Zhiwei Miao* “Therapeutic Options and Treatment Strategies Against COVID-19 in China” Current Organic Synthesis, 2020, 17, 413-414.

  4. Cheng Cheng, Xiaobin Sun, and Zhiwei Miao* “PPh3-Catalyzed Sequential Annulation Reaction to Construct of Cyclopentane-Fused Dihydropyrazolone-pyrrolidinediones” Org. Biomol. Chem. 2020, 18, 5577-5581.

  5. Tianyu Lu, Xuange Zhang, and Zhiwei Miao* “Synthesis of Methylene Cyclopropane-Fused Chromenes and Dihydroquinolines by Sequential [4 + 2]- and [1 + 2]-Annulation” Org. Biomol. Chem. 2020, 18, 3303-3311.

  6. Cheng Cheng, Xiaobin Sun, Zelin Wu, Qianwei Liu, Liqiang Xiong and Zhiwei Miao* “Nitrogen-Containing Lewis Base Catalyzed Regioselective Cyclization of Allene Ketones or α-Methyl Allene Ketone with Unsaturated Pyrazolones” Org. Biomol. Chem. 2019, 17, 3232-3238.

  7. Jiayong Zhang and Zhiwei Miao* “Bisphosphine Catalyzed Sequential [3+2] Cycloaddition and Michael Addition of Ynones with Benzylidenepyrazolones via Dual α’,α’-C(sp3)-H Bifunctionalization to Construct Cyclopentanone-fused Spiro-Pyrazolones” Org. Biomol. Chem. 2018, 16, 9461-9471.

  8. Cheng Cheng, Jiayong Zhang, Xue Wang and Zhiwei Miao* “DBU-Promoted [4+4]-Domino Cycloaddition of Ynones with Benzylidenepyrazolones to Access Eight-Membered Cyclic Ethers” J. Org. Chem. 2018, 83, 5450-5457.

  9. Shuang Liu, Yuming Li, Zhiyu Yin, Qiuli Yu and Zhiwei Miao* “Diastereoselective Synthesis of Adjacent P,C-Stereogenic β-N-Glycosidic Linkaged α-Aminophosphinates” J. Org. Chem. 2017, 82, 2481-2488.

  10. Weiping Zheng, Yuming Li, Jiayong Zhang, Siyi Du and Zhiwei Miao* “High Regio- and Diastereoselective [3+2] Annulation Reaction of Morita-Baylis-Hillman Carbonates with Pyrazolones Catalyzed by Tertiary Phosphines” SYNTHESIS 2017, 49, 3676-3685.

  11. Jiayong Zhang, Cheng Cheng, Dian Wang and Zhiwei Miao* “Regio- and Diastereoselective Construction of Spirocyclopenteneoxindoles through Phosphine-catalyzed [3+2] Annulation of Methyleneindolinone with Alkynoate Derivatives” J. Org. Chem. 2017, 82, 10121-10128.

  12. Yuming Li, Haikun Zhang, Rong Wei and Zhiwei Miao* “Chemo- and Diastereoselective Construction of Indenopyrazolines via a Cascade aza-Michael/Aldol Annulation of Huisgen Zwitterions with 2-Arylideneindane-1,3-diones” Adv. Synth. Catal. 2017, 359, 4158-4164.


Commercialization of Scientific and Research Findings

  1. National Natural Science Foundation of China (No. 22071113)

  2. the Committee of Science and Technology of Tianjin (19YFZCSN00240)

  3. the National Key Research and Development Program of China (2016YFD0201200)