Education   

2012-2017    State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin, China. Received Ph.D. Degree in July, 2017(with  Prof.Qi-Lin Zhou).

2008-2012    China Pharmaceutical University, Nanjing, China. Received B. Sc. Degree in July, 2012.

Academic Career

2021-            Professor (tenure-track),State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, China.

2018-2021    Postdoctoral Associate, Department of Chemistry, The Scripps Research Institute. San Diego, USA. (with Prof. Jin-Quan Yu).

(1)     Organometallic Chemistry

(2)     Transition-Metal Catalysis

(3)     Catalytic Asymmetric Synthesis

Honors & Awards 
2023    Thieme Chemistry Journals Award

2022    National Outstanding Young Talents Program (NSFC)

2021    Nankai University Hundred Young Academic Leaders Program

Selected Publications

1. Tianze Zhang, Shan Jiang, Meng-Ying Qian, Qi-Lin Zhou, Li-Jun Xiao*. Ligand-Controlled Regiodivergent Nickel-Catalyzed Hydroaminoalkylation of Unactivated Alkenes.J. Am. Chem. Soc. 2024, 146, DOI: 10.1021/jacs.3c13060.

2. Jin-Tao Ma, Tianze Zhang, Bo-Ying Yao, Li-Jun Xiao*, Qi-Lin Zhou. Diastereodivergent and Enantioselective Synthesis of Homoallylic Alcohols via Nickel-Catalyzed Borylative Coupling of 1,3-Dienes with Aldehydes. J. Am. Chem. Soc. 2023, 145, 19195−19201.

3. Wei-Guo Xiao, Bin Xuan, Li-Jun Xiao*, Qi-Lin Zhou. Practical Synthesis of Allylic Amines via Nickel-Catalysed Multicomponent Coupling of Alkenes, Aldehydes, and Amides. Chem. Sci. 2023, 14, 8644–8650.

4. Ming-Ming Li, Tianze Zhang, Lei Cheng, Wei-Guo Xiao, Jin-Tao Ma, Li-Jun Xiao*, Qi-Lin Zhou*. Ketone α-Alkylation at the More-Hindered Site. Nat. Commun. 2023, 14, 3326.

5. Biao Wang, Tianze Zhang, Li-Jun Xiao*, Qi-Lin Zhou*. Nickel-Catalyzed Intermolecular Reductive Coupling of Styrene and Its Derivatives with Imines Using Methanol as a Reductant. ACS Catal. 2023, 13, 8692−8699.

6. Biao Wang, Xian-Ming Liu, Kai-Xiang Zhang, Wei-Min Feng, Li-Jun Xiao*, Qi-Lin Zhou*. Diastereoselective and Enantioselective Nickel-Catalyzed Reductive Coupling of Imines and Unactivated Alkenes. CCS Chem. 2023, 5, 814–822.

7. Xiao-Ya Sun, Bo-Ying Yao, Bin Xuan, Li-Jun Xiao*, Qi-Lin Zhou*. Recent Advances in Nickel-Catalyzed Asymmetric Hydrofunctionalization of Alkenes. Chem Catalysis 2022, 2, 1–23.

8. Chao Fan, Xin-Yang Lv, Li-Jun Xiao*, Jian-Hua Xie, Qi-Lin Zhou*. Alkenyl Exchange of Allylamines via Nickel(0)-Catalyzed C−C Bond Cleavage. J. Am. Chem. Soc. 2019, 141, 2889−2893.

9. Lei Cheng, Ming-Ming Li, Li-Jun Xiao*, Jian-Hua Xie, Qi-Lin Zhou*. Nickel(0)-Catalyzed Hydroalkylation of 1,3-Dienes with Simple Ketones. J. Am. Chem. Soc. 2018, 140, 11627–11630.

10. Xin-Yang Lv, Chao Fan, Li-Jun Xiao*, Jian-Hua Xie, Qi-Lin Zhou*. Ligand-Enabled Ni-Catalyzed Enantioselective Hydroarylation of Styrenes and 1,3-Dienes with Arylboronic Acids. CCS Chem. 2019, 1, 328−334.

11. Li-Jun Xiao, Kai Hong, Fan Luo, Liang Hu, William R. Ewing, Kap-Sun Yeung, Jin-Quan Yu*, Pd^II-Catalyzed Enantioselective C(sp³)–H Arylation of Cyclobutyl Ketones Using a Chiral Transient Directing Group, Angew. Chem. Int. Ed. 2020, 59, 9594−9600.

12. Jin-Tang Cheng^#, Li-Jun Xiao^#, Shao-Qun Qian, Zhe Zhuang, An Liu, Jin-Quan Yu*. Palladium(II)-Catalyzed Selective Arylation of Tertiary C–H Bonds of Cyclobutylmethyl Ketones Using Transient Directing Groups. Angew. Chem. Int. Ed. 2022, 61, e202117233.

13. Guowei Kang^#, Li-Jun Xiao^#, Kevin D. Hesp, Chan Woo Huh, Yajing Lian, Paul Richardson, Daniel C. Schmitt, Kai Hong, Jin-Quan Yu*. Synthesis of Highly Substituted Aminotetrahydropyrans Enabled by Stereospecific Multivector C−H Functionalization. Org. Lett. 2023, 25, DOI: 10.1021/acs.orglett.3c01439.

14.  Li-Jun Xiao, Chao-Yue Zhao, Lei Cheng, Bo-Ya Feng, Wei-Min Feng, Jian-Hua Xie, Xiu-Fang Xu*, Qi-Lin Zhou*, Nickel(0)-Catalyzed Hydroalkenylation of Imines with Styrene and Its Derivatives, Angew. Chem. Int. Ed. 2018, 57, 3396−3400.

15. Li-Jun Xiao, Lei Cheng, Wei-Min Feng, Mao-Lin Li, Jian-Hua Xie, Qi-Lin Zhou*, Nickel(0)-Catalyzed Hydroarylation of Styrenes and 1,3-Dienes with Organoboron Compounds, Angew. Chem. Int. Ed. 2018, 57, 461−464.

16. Li-Jun Xiao, Xiao-Ning Fu, Min-Jie Zhou, Jian-Hua Xie, Li-Xin Wang, Xiu-Fang Xu*, Qi-Lin Zhou*, Nickel-Catalyzed Hydroacylation of Styrenes with Simple Aldehydes: Reaction Development and Mechanistic Insights, J. Am. Chem. Soc. 2016, 138, 9, 2957–2960.