EDUCATION

1994-1997,  Department of Chemistry, Hangzhou University, Hangzhou, CHINA. Received Ph.D. degree in June, 1997(with Prof. Yongmin Zhang).

1986-1989,  Department of Chemistry, Henan Normal University, Xinxiang, CHINA. Received M. Sc. Degree in June, 1989

1982-1986,  Department of Chemistry, Henan Normal University, Xinxiang, CHINA. Received B. Sc. Degree in June, 1986

ACADEMIC CAREER              

2011-Now,  Professor, State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

2008-2011,  Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

2002-2008,  Associate Professor, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

1999-2002,  Postdoctoral associate, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.(with Professor Hidenobu Ohmori and Hatsuo Maeda)

1997-1999,  Postdoctoral associate, Institute of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.(with Professor Ruyu Chen).

1989-1994,  Assistant P rofessor and Lecturer, Department of Chemistry, Henan Normal University, Xinxiang, CHINA.

(1) Organophosphorus Chemistry and Sulfur Ylide Chemitry.

(2) Organic Synthetic Chemistry.

(3) Asymmetric Catalysis Base on Organocatalysis.

SELECTED PUBLICATIONS

1. Wei Cai, You Huang* Metal Free Dötz-Type Aminobenzannulation Reaction via 1,1-Dipoles Cross-Coupling Angew. Chem. Int. Ed., 2023, 62, e202310133.

2. Eerqing. Li, Hongxing Jin, Penghao Jia, Xuelin Dong, You Huang* Bifunctional Phosphine Catalyzed Sequential Annulations of Allenoates and Ketimines: Construction of Functionalized Poly-heterocycle Rings Angew. Chem. Int. Ed. 2016, 55, 11591-11594.

3. Xuelin Dong, Ling Liang, Erqing Li, You Huang* Highly Enantioselective Intermolecular Cross Rauhut-Currier Reaction Catalyzed by a Multifunctional Lewis Base Catalyst Angew. Chem. Int. Ed. 2015, 54, 1621-1624.（Hot Paper)

4. Jiaxu Feng, You Huang* Phosphine-Catalyzed Remote 1,7-Addition for Synthesis of Diene Carboxylates ACS Catal., 2020, 10, 3541-3547.

5. Erqing Li, Penghao Jia, Ling Liang, You Huang* Phosphine-Catalyzed Sequential [2+3] and [3+2] Annulation Domino Reaction of γ-Benzyl Substituted Allenoates with α,β-Unsaturated Ketimines To Construct Aza-bicyclo[3,3,0]octane Derivatives  ACS Catal. 2014, 4, 600-603.

6. Jingxiong Lai, Wei Cai, You Huang* Enantioselective phosphine-catalyzed [6 + 1] annulations of α-allyl allenoates with 1,1-bisnucleophiles Chem. Sci., 2024, 15, 11515-11520.

7. Xuling Pan, You Huang* Phosphine-Mediated de Novo Arylamidation of αAllylic Allenoates and Isocyanates via Bicyclo[3.1.0]hexene Access to Aryl Amides Org. Lett. 2025, 27, 6571−6577

8. Xuling Pan, Wei Cai, You Huang* Recent advances in phosphine-me diate d sequential annulations Chin. Chem. Lett. 2025，36,(5), 110628

9. Yiming Zhou, Wei Cai, You Huang* Catalyst-Free Domino Cross-Olefinations and Intramolecular Cyclizations of Morita−Baylis−Hillman Carbonates with SulfurYlides Org. Lett., 2024, 26, 7212–7216.

10. Mengmeng Ma, Jiaxu Feng, Wei Cai, You Huang* Phosphine-Catalyzed Domino Annulation of γ-Vinyl Allenoates: Synthesis of Tetrahydrofuro[3,2-c]quinoline Derivatives Org. Lett., 2024, 26, 4037–4042.

11. Jingxiong Lai, You Huang* A highly diastereoselective (5+1) annulation of allenoates and pyrazolones catalyzed by CH₃OK Chem. Commun., 2024, 60, 2066-2069.

12. Wei Cai, Yanxin Hu, Nan Wang, You Huang* Phosphine mediated formal [5+1] aminobenzannulations of Morita-Baylis-Hillman carbonates with isocyanates Org. Chem. Front., 2024, 11, 7130–7135

13. Jingxiong Lai, You Huang* Phosphine-catalyzed formal Buchner [6+1] annulation:ndenovo construction of cycloheptatrienes Chem. Commun., 2023, 59, 13215-13218.

14. Yanlin He, Wei Cai, You Huang* Lewis-Base-Catalyzed Enantioselective Formal [4 + 2] Annulations of Morita–Baylis–Hillman Carbonates: Access to Tetrahydroquinolines Derivatives Org. Lett., 2023, 25, 3347–3351.

15. Yiming Zhou; You Huang* Cyclopropanation of Propargyl Sulfonium Salts: Highly Diastereoselective Synthesis of Alkynylcyclopropanes ACS Sustainable Chem. Eng. 2022, 10, 15344−15349.

16. Hongxia Ren, Mengmeng Ma, You Huang* Progress in Synthesis of Nitrogen Heterocycles Catalyzed by Chiral Phosphine Chin. J. Org. Chem. 2022, 42(10), 3129-3142.

17. Xiaohu Li, Wei Cai, You Huang* One-Pot Synthesis of 2,3,6-Trisubstituted Pyridines by Phosphine-Catalyzed Annulation of γ-Vinyl Allenoates with Enamino Esters Followed by DDQ-Promoted Oxidative Aromatization Adv. Synth. Catal. 2022, 364(11), 1879-1883

18. Junhui Lin, Yannan Zhu, Wei Cai, You Huang* Phosphine-Mediated Sequential [2+4]/[2+3] Annulation to Construct Pyrroloquinolines Org. Lett. 2022, 24(8), 1593-1597

19. Wei Cai, Yiming Zhou, Yanlin He, You Huang* DABCO catalyzed [4+2] annulations of Morita–Baylis–Hillman carbonates with isocyanates Chem. Commun. 2021, 57(71), 8985-8988

20. Wei Cai, Yiming Zhou, Yanlin He, Kaihong Chen, Cui Yu, and You Huang* Designing and Accurately Developing a [6 + 2] Dipolar Cycloaddition for the Synthesis of Benzodiazocines Org. Lett. 2021, 23, 5430−5434

21. Dan Wang, Junhui Lin, Yannan Zhu, You Huang* De Novo Construction of Substituted Terephthalates via Phosphine Catalyzed Domino Benzannulation Reactions Adv. Synth. Catal. 2021, 363, 1873-1877

22. Wei Cai, Yanlin He, Yiming Zhou, You Huang* Catalyst-Controlled Divergent Intramolecular Cyclizations of Morita−Baylis−Hillman Carbonates J. Org. Chem. 2021, 86, 12267−12276

23. Yiming Zhou; Ning Li; Wei Cai, You Huang* Asymmetric Sequential Corey-Chaykovsky Cyclopropanation/Cloke-Wilson Rearrangement for the Synthesis of 2,3-Dihydrofurans Org. Lett. 2021, 23(22), 8755-8760

24. Xiaohu Li; You Huang* Phosphine-catalyzed sequential (2+3)/(2+4) annulation of γ-vinyl allenoates: Access to the synthesis of chromeno[4,3-: B] pyrroles Chem. Commun. 2021, 57(77), 9934-9937

25. Erqing Li, You Huang* Recent advances in phosphine catalysis involving γ-substituted allenoates Chem. Commun. 2020, 56, 680-694

26. Yannan Zhu, You Huang* Organocatalyzed [3+3] Annulations for the Construction of Heterocycles Synthesis 2020, 52, 1181–1202

27. Jiaxu Feng, Yingying Chen, Wenhui Qin, You Huang* Phosphine-Catalyzed (3 + 2)/(3 + 2) Sequential Annulation of γ‑Vinyl Allenoates: Access to Fused Carbocycles Org. Lett. 2020, 22, 433−437

28. Yiming Zhou, Yu Chen, You Huang* Divergent Domino Reactions of Prop-2-ynylsulfonium Salts: Access to Sulfur-Containing Benzo-Fused Dioxabicyclo[3.3.1]nonanes and Dihydrofuro[2,3‑c]chromenes Org. Lett. 2020, 22, 5941−5946

29. Yannan Zhu, You Huang* Construction of CF3‑Containing Tetrahydropyrano[3,2‑b]indoles through DMAP-Catalyzed [4+1]/[3+3] Domino Sequential Annulation Org. Lett. 2020, 22, 6750−6755

30. Ning Li, You Huang* Phosphine-Catalyzed Sequential [3+3]/Aza-6π-Electrocyclization Reaction of Cross-Conjugated Azatrienes and δ‑Sulfonamido-Allenoates Org. Lett. 2020, 22, 9392−9397