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南开大学元素有机重点实验室

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渠 瑾 教授 博士生导师

Prof. Jin Qu(J. Qu)

Tel:86-22-23503738

E-mail: qujin@nankai.edu.cn

 

 

EDUCATION

  1997-2001   Ph.D., The University of Hong Kong, Hong Kong, CHINA.

  1992-1995   M.Sc., Lanzhou University, Lanzhou, CHINA.

  1988-1992   B.S., Lanzhou University, Lanzhou, CHINA.

ACADEMIC CAREER

2004-             Professor,State Key Laboratory of Elemento-organic Chemistry,
Nankai University, Tianjin, CHINA.

2001-2003     Postdoctoral Fellow, Stanford University, U.S.A.

 

RESEARCH AREAS

Synthetic Methodology Development and Total Synthesis of Bioactive Natural Products

 


HONORS AND AWARDS

2009    Program for New Century Excellent Talents in University

2014    Thieme Chemistry Journals Award

 

SELECTED PUBLICATIONS

  1. Endo-selective Epoxide-opening Cascade for Fast Assembly of the Polycyclic Core Structure of Marine Ladder Polyethers Feng-Xing Li, Shu-Jian Ren, Pei-Fang Li, Peng Yang, Jin Qu* Angew. Chem. Int. Ed. 2020, 59, ASAP (DOI: 10.1002/anie.202007980)

  2. Redox-Neutral αC−H Functionalization of Pyrrolidin-3-ol Cheng-Bo, Yi, Zhi-Ying, She, Yong-Feng Cheng, Jin Qu* Org. Lett. 2018, 20, 668–671.

  3. Molecular Iodine–Mediated a-C–H Oxidation of Pyrrolidines to N,O-Acetals: Synthesis of (±)-Preussin by Late-Stage 2,5-Difunctionalizations of Pyrrolidine. Hao-Jie, Rong, Jun-Jun, Yao, Ji-Kun, Li, Jin Qu* J. Org. Chem. 2017, 82, 5557–5565.

  4. Synthesis of γ-Lactams by Mild, o-Benzoquinone-Induced Oxidation of Pyrrolidines Containing Oxidation-Sensitive Functional Groups Hao-Jie, Rong, Yong-Feng, Cheng, Fan-Fan, Liu, Shu-Jian, Ren, Jin Qu* J. Org. Chem. 2017, 82, 532–540.

  5. Ring-Opening/Expansion Rearrangement of Cycloprop[2,3]inden-1-ols Catalyzed by p-Toluenesulfonic Acid Pei-Fang, Li, Cheng-Bo, Yi, Shu-Jian, Ren, Jin Qu* Adv Synth Catal. 2016, 358, 2088–2092.

  6. Tetraphenylphosphonium Tetrafluoroborate/1,1,1,3,3,3-hexafluoroisopropanol (Ph4PBF4/HFIP) Effecting Epoxide-Initiated Cation-Olefin Polycyclizations Yan Tian, Xin Xu, Lin Zhang, Jin Qu* Org. Lett. 2016, 18, 268–271.

  7. Redox-Triggered α-C–H Functionalization of Pyrrolidines: Synthesis of Unsymmetrically 2,5-Disubstituted Pyrrolidines Yong-Feng Cheng, Hao-Jie Rong, Cheng-Bo Yi, Jun-Jun Yao, and Jin Qu* Org. Lett. 2015, 17, 4758–4761.

  8. Hot Water–Promoted Cyclopropylcarbinyl Rearrangement Facilitates Construction of Homoallylic Alcohols; Pei-Fang, Li, Cheng-Bo, Yi, Jin Qu* Org. Biomol. Chem. 2015, 5012-5021.

  9. Intramolecular Etherification and Polyene Cyclization of p-Activated Alcohols Promoted by Hot Water; Feng-Zhi Zhang, Yan Tian, Guo-Xing Li, Jin Qu* J. Org. Chem. 2015, 80, 1107-1115.

  10. How Does Aqueous Solubility of Organic Reactants Affect a Water-Promoted Reaction?; Yi-Jie Zuo, Jin Qu* J. Org. Chem. 2014, 79, 6832-6839.

  11. Simple and Efficient Synthesis of Tetrahydro-β-Carbolines via the Pictet–Spengler Reaction in 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP); Li-Na, Wang, Su-Li, Shen, Jin Qu* RSC Adv. 2014, 4, 30733−30741.

  12. 1,n-Rearrangement of Allylic Alcohols Promoted by Hot Water: Application to the Synthesis of Navenone B, a Polyene Natural Product; Pei-Fang, Li, Heng-Lu, Wang, Jin Qu* J. Org. Chem. 2014, 79, 3955−3962.

  13. A Catalyst-free One Pot Construction of Skeletons of 5-Methoxyseselin and Alloxanthoxyletin in Water; Jin-Li Cao, Su-Li Shen, Peng Yang, Jin Qu* Org. Lett. 2013, 15, 3856–3859.

  14. Hot Water-Promoted SN1 Solvolysis Reactions of Allylic and Benzylic Alcohols; Zhao-Bing Xu and Jin Qu* Chem. Eur. J. 2013, 19, 314–323.

  15. Two Concise Enantioselective Total Syntheses of (-)-Glabrescol Implicate Alternative Biosynthetic Pathways Starting from Squalene; Peng Yang, Pei-Fang Li, Jin Qu* and Liang-Fu Tang Org. Lett. 2012, 14, 3932–3935.

  16. Enantioselective Friedel–Crafts Reaction between Phenols and N-Tosylaldimines Catalyzed by Leucine-Derived Bifunctional Catalyst; Guo-Xing Li and Jin Qu* Chem. Commun. 2012, 48, 5518–5520.

  17. Backbone Modification of b-Hairpin-Forming Tetrapeptides in Asymmetric Acyl Transfer Reactions; Peng Chen and Jin Qu* J. Org. Chem. 2011, 76, 2994–3004. (Featured Article)

  18. Desymmetrization of meso-1,2-Diols via the Dynamic Kinetic Resolution of Its Monodichloroacetates; Jin-Li Cao and Jin Qu* J. Org. Chem. 2010, 75, 3663–3670.

  19. Friedel-Crafts Alkylation of Arenes with Epoxides Promoted by Fluorinated Alcohols or Water; Guo-Xing Li and Jin Qu* Chem. Commun. 2010, 2653–2655.

  20. Boiling water-catalyzed neutral and selective N-Boc deprotection; Jia Wang, Yan-Liang Liang and Jin Qu* Chem. Commun. 2009, 5144–5146.

  21. Kinetic Resolution of Racemic Alcohols Using Thioamide Modified 1-Methyl-histidine Methyl Ester; Xue-Li Geng, Jia Wang, Guo-Xing Li, Peng Chen, Shu-Fang Tian, and Jin Qu* J. Org. Chem. 2008, 73, 8558–8562.

  22. Hot Water Promoted Ring-opening of Epoxides and Aziridines by Water and Other Nucleophiles; Zhi Wang, Yong-Tao Cui, Zhao-Bing Xu, and Jin Qu* J. Org. Chem. 2008, 73, 2270–2274. (Highlighted in Organic Chemistry Portal)