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南开大学元素有机重点实验室

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叶萌春 研究员     

Prof. Meng-Chun Ye (M.-C. Ye)        

Tel: 86-22-23504701        

E-mail: mcye@nankai.edu.cn

Group Home Page: http://www.yechem.cn        


 

Education   

2001-2006    Shanghai Institute of Organic Chemistry, CAS. Received Ph.D. Degree in July, 2006 (with Prof. Yong Tang)  

1997-2001    Department of Chemistry, Lanzhou University, Lanzhou, China.Received B. Sc. Degree in July, 2001.  

 

Academic Career                                

2014-presentProfessor, State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin, CHINA.

2009-2013Research Associate, Department of Chemistry, The Scripps Research Institute, Sandiego, USA. (with Prof. Jin-Quan Yu).

2006-2009, Postdoctoral Researcher, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, USA. (with Prof. HengmingKe).


Research Areas

(1)     Organic synthesis

(2)     Transition metal catalysis.


Honors & Awards 
2017    Thieme Chemistry Journal Award


Selected Publications

  1. A Directive Ni Catalyst Overrides Conventional Site-Selectivity in Pyridine C–H Alkenylation. Tao Zhang, Yu-Xin Luan, Nelson Y. S. Lam, Jiang-Fei Li, Yue Li, Mengchun Ye,* Jin-Quan Yu*Nat. Chem. 2021, 13, 1207-1213.

  2. Ni-Catalyzed Hydroaminoalkylation of Alkynes with Amines. Wei-Wei Yao, Ran Li, Hao Chen, Ming-Kai Chen, Yu-Xin Luan,* Yi Wang, Zhi-Xiang Yu,* Mengchun Ye* Nat. Comm. 2021, 12, 3800.

  3. Construction 7-Membered Ring via Ni-Al Bimetal-Enabled C-H Cyclization for Synthesis of Tricyclic Imidazoles. Jiang-Fei Li, Wei-Wei Xu, Rong-Hua Wang, Yue Li, Ge Yin, Mengchun Ye* Nat. Comm. 2021, 12, 3070.

  4. Carbamoyl Fluoride-Enabled Enantioselective Ni-Catalyzed Carbocarbamoylation of Unactivated Alkenes. Yue Li, Feng-Ping Zhang, Rong-Hua Wang, Shao-Long Qi, Yu-Xin Luan,* and Mengchun Ye* J. Am. Chem. Soc. 2020, 142, 19844−19849.

  5. Enantioselective Twofold CH Annulation of Formamides and Alkynes without Built-in Chelating Groups. Hao Chen, Yin-Xia Wang, Yu-Xin Luan, Mengchun Ye* Angew. Chem. Int. Ed. 2020, 59, 9428-9432.

  6. Chiral Aluminum-Controlled Ni-catalyzed Enantioselective Synthesis of Indenes via C-CN Bond Activation. Tao Zhang, Yu-Xin Luan, Su-Juan Zheng, Qian Peng*, Mengchun Ye* Angew. Chem. Int. Ed. 2020, 59, 7439-7443.

  7. Ligand-Promoted Fe(III)-Catalyzed Hydrofluorination of Alkenes. Yongtao Xie, Peng-Wei Sun, Yuxin Li, Siwei Wang, Mengchun Ye*, Zhengming Li* Angew. Chem. Int. Ed. 2019, 58, 7097-7101.

  8. Enantioselective Ni−Al Bimetallic Catalyzed exo-Selective C−H Cyclization of Imidazoles with Alkenes. Yin-Xia Wang, Shao-Long Qi, Yu-Xin Luan, Xing-Wang Han, Shan Wang, Hao Chen, Mengchun Ye* J. Am. Chem. Soc. 2018, 140, 5360−5364.

  9. Brønsted Acid Enabled Nickel-Catalyzed Hydroalkenylation of Aldehydes with Styrene and Derivatives. Xing-Wang Han, Tao Zhang, Yan-Long Zheng, Wei-Wei Yao, Jiang-Fei Li, You-Ge Pu, Mengchun Ye*, Qi-Lin Zhou. Angew. Chem. Int. Ed. 2018, 57, 5068-5071.

  10.  Ni−Al Bimetallic Catalyzed Enantioselective Cycloaddition of Cyclopropyl Carboxamide with Alkyne. Qi-Sheng Liu, De-Yin Wang, Zhi-Jun Yang, Yu-Xin Luan, Jin-Fei Yang, Jiang-Fei Li, You-Ge Pu, Mengchun Ye* J. Am. Chem. Soc. 2017, 139, 18150-18153.

  11. Amide-Ligand-Controlled Highly para-Selective Arylation of Monosubstituted Simple Arenes with Arylboronic Acids. Yu-Xin Luan, Tao Zhang, Wei-Wei Yao, Ke Lu, Lu-Yao Kong, Yu-Tong Lin, Mengchun Ye* J. Am. Chem. Soc. 2017, 139, 1786-1789

  12. Ligand-Accelerated Direct C-H Arylation of BINOL: A Rapid One-Step Synthesis of Racemic 3,3’-Diaryl BINOLs. Jin-Fei Yang, Rong-Hua Wang, Yin-Xia Wang, Wei-Wei Yao, Qi-Sheng Liu, Mengchun Ye* Angew. Chem. Int. Ed. 2016, 55, 14116-14120.

  13. Iron-Catalyzed Regioselective Transfer Hydrogenative Couplings of Unactivated Aldehydes with Simple Alkenes. Yan-Long Zheng, Yan-Yao Liu, Yi-Mei Wu, Yin-Xia Wang, Yu-Tong Lin, Mengchun Ye* Angew. Chem. Int. Ed. 2016, 55, 6315-6318.

  14. Ni/Brfnsted Acid-Catalyzed Redox-Neutral Coupling of 1,3-Dienes and Aldehydes for Synthesis of Dienols. Xing-Wang Han†, Tao Zhang†, Wei-Wei Yao, Hao Chen, Mengchun Ye* CCS Chem. 2020, 2, 955-963.

  15. Bimetallic anchoring catalysis for C–H and C–C activation. Jiang-Fei Li, Yu-Xin Luan*, Mengchun Ye* Sci China Chem. 2021, 64, 1923–1937.

  16. Recent advances in Ni−Al bimetallic catalysis for unreactive bond transformation. Yin-Xia Wang, Mengchun Ye* Sci. China Chem. 2018, 61, 1004-1013.