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南开大学元素有机重点实验室

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何刚          特聘研究员 博士生导师                      
                     
      Prof. Gang He (G. He)                      
      E-mail:       hegang@nankai.edu.cn
                                           
                     

 

EDUCATION    

2003–2009


Organic Chemistry, State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of

Organic Chemistry, CAS, China. Received Ph.D. degree in April, 2009(with Prof. Dawei Ma)

1999–2003
Department of Chemistry, Nankai University, Tianjin, China. Received B. Sc. Degree in June, 2003.
     
 

              ACADEMIC CAREER  
   
    2015-Date
Professor (tenure track), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, China.
    2010-2014
Postdoctoral associate, Department of Chemistry, The Pennsylvania State University (with Prof. Gong Chen).
    
RESEARCH AREAS

(1) C-H functionalization methodology development.
(2)  Total synthesis of bioactive natural products.
 

SELECTED PUBLICATIONS
                   
 
  1.      Benzazetidine synthesis via palladium-catalysedintramolecular C−H amination. Gang He*, Gang Lu, ZhengweiGuo, Peng Liu*& Gong Chen*. Nat. Chem.2016, online, DOI:10.1038/NCHEM.2585.

  2.       Use of a readily removable auxiliary group for the synthesis of pyrrolidones by the palladium-catalyzed intramolecular amination of  unactivated γC(sp3)-H bonds. Gang He, Shu-Yu Zhang, William A. Nack, and Gong Chen*. Angew. Chem. Int. Ed.  2013, 2, 11124-11128. 

  3.       Highly efficient syntheses of azetidines, pyrrolidines and indolines via palladium-catalyzed intramolecular amination of C(sp3)-H and C(sp2)-H Bonds atγand δ positions.Gang He, Yingsheng Zhao, Shuyu Zhang, Chengxi Lu, and Gong Chen*. J. Am. Chem. Soc.2012, 134, 3-6. 

  4.       Apractical strategy for structural diversification of aliphatic scaffolds via Pd-catalyzed picolinamide-directed remote functionalization of  unactivated C(sp3)-H bonds.Gang He and Gong Chen*. Angew. Chem. Int. Ed. 2011, 50, 5192-5196.