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元素有机化学国家重点实验室(南开大学)

骨干研究人员

研究队伍


贺峥杰  教授  博士生导师

Prof. Zheng-Jie He(Z.-J. He)

Tel: 86-22-23501520

E-mail: zhengjiehe@nankai.edu.cn

Group Home Page:  http://hez.nankai.edu.cn

 


EDUCATION

1989-1994

Institute of Elemento-Organic Chemistry, Nankai University, Tianjin,
C
hina. Received Ph.D. degree in June, 1994 (with Prof. Zheng-Ming Li).
1985-1989

Department of Chemistry, Central China Normal University, Wuhan,
C
hina. Received B. Sc. Degree in June, 1989.

 


ACADEMIC CAREER

2004-Date
Professor, Department of Chemistry, Nankai University, Tianjin, CHINA.
2003-2004

Postdoctoral associate, Department of Industrial and Physical Pharmacy, Pharmacy School,
Purdue University, USA
(with Prof. Shuang Liu).
1999-2003

Postdoctoral associate, Department of Chemistry, Marquette University, USA
(
with Prof. William A. Donaldson and Prof. Chae S. Yi).
1998-1999

Postdoctoral associate, Department of Chemistry, University of Pretoria, South Africa
(
with Prof. Tomasz A. Modro).
1994-1998


Lecturer (1994-1996) and Associate Professor (1996-1998), Institute of Elemento-organic
Chemistry,
Nankai University, Tianjin, China.

RESEARCH AREAS

(1) Organophosphorus chemistry with emphasis on P-ylide chemistry.

(2) Organic synthetic chemistry mainly focused on phosphorus reagents-mediated new reactions and synthetic methods.

(3) Medicinal chemistry mainly focused on the discovery of anticancer agents and the development of radio-active imaging agents.

 

SELECTED PUBLICATIONS

  1. Changjiang Yang, Wei Liu, Zijian He, Zhengjie He*, Divergent reactivity of nitrocyclopropanes with Huisgen zwitterions and facile syntheses of 3-alkoxy pyrazolines and pyrazoles, Org. Lett. 2016, 18, 4936-4939.
  2. Zifeng, Wei Liu, Danyang Wang, Zhengjie He*, Phosphine-catalyzed (4+1) annulation of o-hydroxyphenyl and o-aminophenyl ketones with allylic carbonates: syntheses and transformations of 3-hydroxy-2,3-disubstituted dihydrobenzofurans and indolines, J. Org. Chem. 2016, 81, 4690-4700.
  3. Changjiang Yang, Xiangyu Chen, Tong Tang, Zhengjie He*, Annulation reaction of 3-acylmethylidene oxindoles with Huisgen zwitterions and its applications in the syntheses of pyrrolo[4,3,2-de]quinolinones and marine alkaloids Ammosamides, Org. Lett. 2016, 18, 1486-1489.
  4. Rong Zhou*, Kai Zhang, Yusong Chen, QiangMeng, Yiyi Liu, Ruifeng Li, Zhengjie He*, P(NMe2)3-mediated reductive [1+4] annulation of isatins with enones: facile synthesis of spirooxindole-dihydrofurans, Chem. Commun. 2015, 51, 14663-14666.
  5. Changjiang Yang, Juanjuan Li, Rong Zhou, Xiangyu Chen, YunpengGao, Zhengjie He*, Facile synthesis of spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines and their fungicidal activity, Org. Biomol. Chem. 2015, 13, 4869-4878.
  6. Rong Zhou, Changjiang Yang, Yiyi Liu, Ruifeng Li, Zhengjie He*, Diastereoselective synthesis of functionalized spirocyclopropyl oxindoles via P(NMe2)3-mediated reductive cyclopropanation, J. Org. Chem. 2014, 79, 10709-10715.
  7. Mei Yang, Tianyi Wang, Shixuan Cao, Zhengjie He*, Phosphine-catalyzed [4+1] annulation of 1,3-(aza)dienes with maleimides: highly efficient construction of azaspiro[4.4]nonenes, Chem. Commun. 2014, 50, 13506-13509.
  8. Rong Zhou, Jianfang Wang, Jia Yu, Zhengjie He*, Highly chemoselectiveRauhut-Currier reaction between maleimides and enones and dual phosphine-mediated one-pot synthesis of bicyclic and polycyclic skeletons, J. Org. Chem. 2013, 78, 10596-10604.
  9. Rongshun Chen, Silong Xu, Liyi Wang, Yuhai Tang, Zhengjie He*, Distinct reactivity of Morita-Baylis-Hillman acetates as a novel C2 component in amine-catalyzed [2+2+2] and [2+4] annulations, Chem. Commun. 2013, 49, 3543-3545.
  10. JunjunTian, Zhengjie He*, Phosphine-catalyzed [3+2] annulation of α-substituted allenoates with ester-activated α-unsaturated imines: a novel variation of the Lu [3+2] cycloadditionreaction, Chem. Commun. 2013, 49, 2058-2060.
  11. Rong Zhou, Jianfang Wang, Chong Duan, Zhengjie He*, Phosphine-triggered tandem annulation between Morita-Baylis-Hillman carbonates and dinucleophiles: facile syntheses of oxazepanes, thiazepanes, and diazepanes, Org. Lett. 2012, 14, 6134-6137.
  12. Silong Xu, Rongshun Chen, Zifeng Qin, Guiping Wu, Zhengjie He*, Divergent amine-catalyzed [4+2] annulation of Morita-Baylis-Hillman allylicacetates with electron-deficient alkenes, Org. Lett. 2012, 14, 996-999.